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Summary Expression Phenotypes Gene Literature (10) GO Terms (32) Nucleotides (109) Proteins (39) Interactants (81) Wiki
XB-GENEPAGE-1012023
???displayGene.symbol???:
 lrrc8a

???displayGene.name???: 
leucine rich repeat containing 8 VRAC subunit A

???displayGene.synonyms???
agm5 , lrrc8 , swell1 ( Nomenclature history )

???displayGene.geneFunction???
Leucine-rich repeat (LRR) protein associated with apoptosis in muscle tissue

AI Protein Function :
The lrrc8a gene encodes a component of volume-regulated anion channels. The protein functions as a swelling-activated chloride channel subunit. It localizes to the plasma membrane. Expression is found ...[+]


InterPro :
Leu-rich rpt, Leu-rich rpt typical-subtyp, LRR dom sf, LRR domain-containing, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
agammaglobulinemia [+]

MIM:
AGAMMAGLOBULINEMIA 1, AUTOSOMAL RECESSIVE; AGM1 [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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