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Proc Natl Acad Sci U S A 2011 Feb 15;1087:2915-20. doi: 10.1073/pnas.1019645108.
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Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning.

Fakhro KA , Choi M , Ware SM , Belmont JW , Towbin JA , Lifton RP , Khokha MK , Brueckner M .


PubMed ID: 21282601
PMC ID: PMC3041108
Article link: Proc Natl Acad Sci U S A
Grant support: [+]

Species referenced: Xenopus
Genes referenced: aldh1a1 cryzl1 dnah9 galnt11 gdf7 greb1 grik1 ift88 igfbp5 kyat1 laptm5 lrrc8a myh6 nek2 nup188 pdgfc pitx2 rock2 rpsa runx2 smarcal1 tgfbr2 tgfbr2l tpk1 trat1
GO keywords: heart looping [+]
Morpholinos: aldh1a1 MO1 cryzl1 MO1 dnah9 MO1 galnt11 MO1 gdf7 MO1 greb1 MO1 grik1 MO1 ift88 MO3 igfbp5 MO1 kyat1 MO1 laptm5 MO1 lrrc8a MO1 myh6 MO1 nek2 MO1 nup188 MO1 pdgfc MO1 rock2 MO1 runx2 MO1 smarcal1 MO1 tgfbr2 MO1 tpk1 MO1 trat1 MO1

Disease Ontology terms: visceral heterotaxy

Article Images: [+] show captions
References [+] :
Avidor-Reiss, Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. 2004, Pubmed