Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-27289

Xtr Wt + chmp7 CRISPR, Edwards NA et al. (2025)

Experiment + Assay: Xtr Wt + chmp7 CRISPR + NF44 (immunohistochemistry)
Background: Xtr.inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR chmp7 gRNA1 chmp7
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 44  
Anatomical Phenotypes: abnormal esophagus morphology, abnormal trachea morphology, abnormal tracheoesophageal septum
Human Disease Associations: esophageal atresia, esophageal atresia/tracheoesophageal fistula
Source: Fig. 2c r1c3
Article: XB-ART-61390, PubMed