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XB-PHENO-27151

Xla wt +tcf7l1-delta_ctnnb1-GR, Bou-Rouphael J et al. (2024)

Experiment + Assay: Xla wt +tcf7l1-delta_ctnnb1-GR + NF45 (in situ hybridization)
Background: Xla.Portsmouth1EXRC
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
transgenesis   tcf7l1.L
NF stage 4 (8-cell)
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 45  
Expression Phenotypes (4):
decreased amount atoh1.L expression in rhombomere R1
increased amount barhl1.L expression in rhombomere R1
increased amount neurod1.L expression in rhombomere R1
increased amount pax6.L expression in rhombomere R1
Source: Fig 2 A a a' a'', b b' b'', c; B abcd
Article: XB-ART-60787, PubMed