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XB-PHENO-25959

Xla Wt + prdm15 MO + GFP, Mann N et al. (2021)

Experiment + Assay: Xla Wt + prdm15 MO + GFP + NF35/36 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
lineage tracer GFP
NF stage 2 (2-cell)
morpholino injection prdm15 MO1 prdm15 (Xla)
 NF stage 4 (8-cell) ventral vegetal hemisphere blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 35 and 36  
Expression Phenotypes (1):
decreased amount fxyd2.L expression in pronephric kidney
Human Disease Associations: Galloway-Mowat syndrome 1
Source: Fig. 4. ABC
Article: XB-ART-57819, PubMed