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XB-PHENO-25871

Xla Wt + capn2 MO, Blue EE et al. (2023)

Experiment + Assay: Xla Wt + capn2 MO + NF43-45 (immunohistochemistry)
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection capn2 MO2 capn2 (Xla)
 NF stage 4 (8-cell) blastomere D2
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 43 to NF stage 45 Tnnt2 Ab1
Anatomical Phenotypes: abnormal cardiac ventricle morphology , decreased size of the heart
Human Disease Associations: hypoplastic left heart syndrome
Source: Fig. S3. B
Article: XB-ART-60264, PubMed