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XB-PHENO-25870

Xla Wt + capn2 CRISPR + GFP, Blue EE et al. (2023)

Experiment + Assay: Xla Wt + capn2 CRISPR + GFP + NF43-45 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
lineage tracer GFP
NF stage 8 blastomere D2
CRISPR capn2 gRNA1 capn2 (Xla)
 NF stage 8 blastomere D2
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 43 to NF stage 45  
Anatomical Phenotypes: abnormal cardiac ventricle morphology , decreased size of the heart
Human Disease Associations: hypoplastic left heart syndrome
Source: Fig. 3. B, F
Article: XB-ART-60264, PubMed