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XB-PHENO-25487

Xla Wt + lrp2 MO, Kowalczyk I et al. (2021)

Experiment + Assay: Xla Wt + lrp2 MO + NF16 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection lrp2 MO1 lrp2.L
 NF stage 4 (8-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 16  
Anatomical Phenotypes: abnormal apical constriction, abnormal development of optic vesicle
Expression Phenotypes (1):
decreased amount actb.L expression in neural plate
Source: Fig.3.A,A1,C,E,C1,J
Article: XB-ART-57750, PubMed