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XB-PHENO-24844

Xla Wt + cdkn1a (cip1), Naylor RW et al. (2009)

Experiment + Assay: Xla Wt + cdkn1a (cip1) + NF41 (immunohistochemistry)
Background: Xla.Cambridge
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection cdkn1a.L cdkn1a.L
 NF stage 4 (8-cell) blastomere V2
lineage tracer Bgal
NF stage 4 (8-cell) blastomere V2
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 41 to NF stage 41 Kidney Ab2
immunohistochemistry NF stage 41 to NF stage 41 Kidney Ab1
Anatomical Phenotypes: abnormal pronephric kidney , abnormal pronephric tubule morphology , decreased size of the distal tubule , decreased size of the proximal tubule
Source: Fig. 2C
Article: XB-ART-44366, PubMed