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XB-PHENO-16440

Xla WT + rbpj-DBM RNA [unilateral], Solini GE et al. (2020)

Experiment + Assay: Xla WT + rbpj-DBM RNA [unilateral] + NF 15-NF 35
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection   notch1.L
NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 15 to NF stage 35 and 36  
Anatomical Phenotypes: decreased cell population proliferation in spinal cord
Expression Phenotypes (1):
decreased amount pcna.L expression in neural plate
Source: Fig 4 G H
Article: XB-ART-56609, PubMed