organ system cancer

Literature (72)

Literature for DOID 0050686: organ system cancer

Xenbase Articles Publications associated with this Disease Ontology entry or its descendants

:
(

Denotes literature images)

Kinetic properties of nuclear transport conferred by the retinoblastoma (Rb) NLS., Hu W,Kemp BE,Jans DA, J Cell Biochem. July 1, 2005; 95(4):0730-2312.
AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer., Zhang JS,Gong A,Cheville JC,Smith DI,Young CY, Genes Chromosomes Cancer. July 1, 2005; 43(3):1045-2257.
Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation., Abkevich V,Zharkikh A,Deffenbaugh AM,Frank D,Chen Y,Chen Y,Shattuck D,Skolnick MH,Gutin A,Tavtigian SV, J Med Genet. July 1, 2004; 41(7):1468-6244.
Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome., Grand EK,Grand FH,Chase AJ,Ross FM,Corcoran MM,Oscier DG,Cross NC, Genes Chromosomes Cancer. May 1, 2004; 40(1):1045-2257.
Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E,Du YZ,Mullor JL,Casas E,Allen WP,Gillessen-Kaesbach G,Roeder ER,Ming JE,Ruiz i Altaba A,Muenke M, Proc Natl Acad Sci U S A. November 11, 2003; 100(23):1091-6490.
Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning., Davis RL,Turner DL, Oncogene. December 20, 2001; 20(58):0950-9232.
Notch in vertebrates., Robey E, Curr Opin Genet Dev. August 1, 1997; 7(4):0959-437X.
Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor., Tsutsumi M,Zhou W,Millar RP,Mellon PL,Roberts JL,Flanagan CA,Dong K,Gillo B,Sealfon SC, Mol Endocrinol. July 1, 1992; 6(7):1944-9917.
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis., Kälin RE,Kretz MP,Meyer AM,Kispert A,Heppner FL,Brändli AW, Dev Biol. May 15, 2007; 305(2):1095-564X.
Non-transcriptional control of DNA replication by c-Myc., Dominguez-Sola D,Ying CY,Grandori C,Ruggiero L,Chen B,Li M,Galloway DA,Gu W,Gautier J,Dalla-Favera R, Nature. July 26, 2007; 448(7152):0143-5221.
The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression., Pittman AM,Naranjo S,Webb E,Broderick P,Lips EH,van Wezel T,Morreau H,Sullivan K,Fielding S,Twiss P,Vijayakrishnan J,Casares F,Qureshi M,Gómez-Skarmeta JL,Houlston RS, Genome Res. June 1, 2009; 19(6):1549-5469.
Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled., Grandy D,Shan J,Zhang X,Rao S,Akunuru S,Li H,Zhang Y,Zhang Y,Alpatov I,Zhang XA,Lang RA,Shi DL,Zheng JJ, J Biol Chem. June 12, 2009; 284(24):1083-351X.
An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis., Kälin RE,Bänziger-Tobler NE,Detmar M,Brändli AW, Blood. July 30, 2009; 114(5):1528-0020.
Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts., Cross MK,Powers MA, Dis Model Mech. January 1, 2009; 2(11-12):1754-8411.
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate., Li Y,Trojer P,Xu CF,Cheung P,Kuo A,Drury WJ,Qiao Q,Neubert TA,Xu RM,Gozani O,Reinberg D, J Biol Chem. December 4, 2009; 284(49):1083-351X.
Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease., Dubaissi E,Papalopulu N, Dis Model Mech. March 1, 2011; 4(2):1754-8411.
Epigenetic reprogramming of breast cancer cells with oocyte extracts., Allegrucci C,Rushton MD,Dixon JE,Sottile V,Shah M,Kumari R,Watson S,Alberio R,Johnson AD, Mol Cancer. January 13, 2011; 10(1):1476-4598.
SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton., Langdon Y,Tandon P,Paden E,Duddy J,Taylor JM,Conlon FL, Development. March 1, 2012; 139(5):1477-9129.
Xenopus as a model system for the study of GOLPH2/GP73 function: Xenopus GOLPH2 is required for pronephros development., Li L,Wen L,Gong Y,Mei G,Liu J,Chen Y,Chen Y,Peng T, PLoS One. January 1, 2012; 7(6):1932-6203.
Isthmin inhibits glioma growth through antiangiogenesis in vivo., Yuan B,Xian R,Ma J,Chen Y,Chen Y,Lin C,Song Y, J Neurooncol. September 1, 2012; 109(2):1573-7373.
Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A,Valensin S,Rossi M,Tunici P,Verani M,De Rosa A,Giordano C,Varrone M,Nencini A,Pratelli C,Benicchi T,Bakker A,Hill J,Sangthongpitag K,Pendharkar V,Liu B,Ng FM,Then SW,Jing Tai S,Cheong SM,He X,Caricasole A,Salerno M, Mol Cancer Ther. July 1, 2013; 12(7):1538-8514.
ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel., Wei X,Sun H,Yan H,Zhang C,Zhang S,Liu X,Hua N,Ma X,Zheng J, Cancer Biol Ther. May 1, 2013; 14(5):1555-8576.
Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG,Predes D,Fonseca BF,Cerqueira DM,Reis AH,Dudenhoeffer AC,Borges HL,Mendes FA,Abreu JG, J Biol Chem. December 19, 2014; 289(51):1083-351X.
Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF,Predes D,Cerqueira DM,Reis AH,Amado NG,Cayres MC,Kuster RM,Oliveira FL,Mendes FA,Abreu JG, PLoS One. March 16, 2015; 10(3):1932-6203.
Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA,Hardwick LJ,Papkovskaia TD,Thiele CJ,Philpott A, Dis Model Mech. May 1, 2015; 8(5):1754-8411.
A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A,Liu B,Liang H,Wei C,Guindani M,Lu Y,Liang S,St John LS,Molldrem J,Nagarajan L, Oncotarget. December 30, 2014; 5(24):1949-2553.
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis., Van Nieuwenhuysen T,Naert T,Tran HT,Van Imschoot G,Geurs S,Sanders E,Creytens D,Van Roy F,Vleminckx K,Vleminckx K, Oncoscience. May 19, 2015; 2(5):2331-4737.
9B.03: A NOVEL INSERTIONAL SOMATIC KCNJ5 MUTATION IN AN AUSTRALIAN PATIENT WITH AN ALDOSTERONE PRODUCING ADENOMA., Xu S,Hardege I,Murthy M,Gordon R,Stowasser M,OʼShaughnessy K, J Hypertens. June 1, 2015; 33 Suppl 1:1473-5598.
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer., Puvirajesinghe TM,Bertucci F,Jain A,Scerbo P,Belotti E,Audebert S,Sebbagh M,Lopez M,Brech A,Finetti P,Charafe-Jauffret E,Chaffanet M,Castellano R,Restouin A,Marchetto S,Collette Y,Gonçalvès A,Macara I,Birnbaum D,Kodjabachian L,Johansen T,Borg JP, Nat Commun. January 12, 2016; 7:2041-1723.
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis., Naert T,Colpaert R,Van Nieuwenhuysen T,Dimitrakopoulou D,Leoen J,Haustraete J,Boel A,Steyaert W,Lepez T,Deforce D,Willaert A,Creytens D,Vleminckx K,Vleminckx K, Sci Rep. October 14, 2016; 6:2045-2322.
TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models., Naert T,Van Nieuwenhuysen T,Vleminckx K,Vleminckx K, Genesis. January 1, 2017; 55(1-2):1526-968X.
Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ,Xie SX,Chen YT,Chen YT,Xue JL,Zhang CJ,Zhu F, World J Gastroenterol. September 7, 2016; 22(33):2219-2840.
TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer., Yan L,Li Q,Yang J,Qiao B, J Cell Biochem. February 1, 2018; 119(2):0730-2312.
Overexpression of TPX2 is associated with progression and prognosis of prostate cancer., Zou J,Huang RY,Jiang FN,Chen DX,Wang C,Wang C,Wang C,Han ZD,Liang YX,Zhong WD, Oncol Lett. September 1, 2018; 16(3):1792-1074.
CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs., Naert T,Vleminckx K,Vleminckx K, Drug Discov Today Technol. August 1, 2018; 28:1740-6749.
TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z,Zheng B,Li J,Lv X,Zhang H,Yu F,Kong L,Li Y,Yu M,Fang L,Liang B, Biomed Pharmacother. November 1, 2018; 107:0753-3322.
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R, Biochem Biophys Res Commun. December 9, 2018; 507(1-4):1090-2104.
Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer., Dimitrakopoulou D,Tulkens D,Van Vlierberghe P,Vleminckx K,Vleminckx K, Front Physiol. January 1, 2019; 10:1664-042X.
ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer., Daulat AM,Finetti P,Revinski D,Silveira Wagner M,Camoin L,Audebert S,Birnbaum D,Kodjabachian L,Borg JP,Bertucci F, Br J Cancer. April 1, 2019; 120(9):0007-0920.
Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Chen M,Neul C,Schaeffeler E,Frisch F,Winter S,Schwab M,Koepsell H,Hu S,Laufer S,Baker SD,Sparreboom A,Nies AT, Clin Pharmacol Ther. January 1, 2020; 107(1):1532-6535.
Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P,Kujawa KA,Cortez AJ,Lisowska KM, Diagnostics (Basel). September 14, 2019; 9(3):2075-4418.
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN,Aguero TH,Owens DA,Kurtenbach S,Field MG,Durante MA,Rodriguez DA,King ML,Harbour JW, Sci Adv. September 18, 2019; 5(9):2375-2548.
Identification of Drivers of Aneuploidy in Breast Tumors., Pfister K,Pipka JL,Chiang C,Liu Y,Clark RA,Keller R,Skoglund P,Guertin MJ,Hall IM,Stukenberg PT, Cell Rep. May 29, 2018; 23(9):2211-1247.
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis., Naert T,Dimitrakopoulou D,Tulkens D,Demuynck S,Carron M,Noelanders R,Eeckhout L,Van Isterdael G,Deforce D,Vanhove C,Van Dorpe J,Creytens D,Vleminckx K,Vleminckx K, Oncogene. March 1, 2020; 39(13):0950-9232.
Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning., Reis AH,Sokol SY, Development. May 27, 2020; 147(10):1477-9129.
Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors., Prevost MS,Bouchenaki H,Barilone N,Gielen M,Corringer PJ, Cell Mol Life Sci. February 1, 2021; 78(3):1420-9071.
Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M,Shulepko M,Osmakov D,Andreev Y,Sudarikova A,Vasileva V,Pavlyukov MS,Latyshev YA,Potapov AA,Kirpichnikov M,Shenkarev ZO,Lyukmanova E, Cancers (Basel). July 8, 2020; 12(7):2072-6694.
Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma., Kuznetsoff JN,Owens DA,Lopez A,Rodriguez DA,Chee NT,Kurtenbach S,Bilbao D,Roberts ER,Volmar CH,Wahlestedt C,Brothers SP,Harbour JW, Mol Cancer Res. February 1, 2021; 19(2):1557-3125.
Allosteric regulation of mammalian Na+/I- symporter activity by perchlorate., Llorente-Esteban A,Manville RW,Reyna-Neyra A,Abbott GW,Amzel LM,Carrasco N, Nat Struct Mol Biol. June 1, 2020; 27(6):1545-9985.
Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.
Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P, Genesis. February 1, 2021; 59(1-2):1526-968X.
Use of Xenopus laevis cell-free extracts to study BRCA2 role in chromosome alignment., El Dika M, DNA Repair (Amst). April 1, 2021; 100:1568-7856.
BRCA1-BARD1 regulates transcription through BRD4 in Xenopus nucleoplasmic extract., Barrows JK,Fullbright G,Long DT, Nucleic Acids Res. April 6, 2021; 49(6):1362-4962.
High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability., Matson DR,Denu RA,Zasadil LM,Burkard ME,Weaver BA,Flynn C,Stukenberg PT, BMC Cancer. February 23, 2021; 21(1):1471-2407.
Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus., Moreno MM,Barrell WB,Godwin A,Guille M,Liu KJ,Liu KJ, Gene Expr Patterns. June 1, 2021; 40:1567-133X.
Modeling endoderm development and disease in Xenopus., Edwards NA,Zorn AM, Curr Top Dev Biol. January 1, 2021; 145:1557-8933.
Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide., Fuchs RP,Isogawa A,Paulo JA,Onizuka K,Takahashi T,Amunugama R,Duxin JP,Fujii S, Elife. July 8, 2021; 10:2050-084X.
Weight of Evidence and Human Relevance Evaluation of the Benfluralin Mode of Action in Rats (Part II): Thyroid carcinogenesis., Strupp C,Quesnot N,Weber-Parmentier C,Richert L,Bomann WH,Singh P, Regul Toxicol Pharmacol. November 1, 2020; 117:1096-0295.
Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells., Okuno H,Okano H, Regen Ther. August 24, 2021; 18:2352-3204.
Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H,Lee H,Sun R,Niehrs C, J Biol Chem. February 1, 2022; 298(2):1083-351X.
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders., Martin M,Vermeiren S,Bostaille N,Eubelen M,Spitzer D,Vermeersch M,Profaci CP,Pozuelo E,Toussay X,Raman-Nair J,Tebabi P,America M,De Groote A,Sanderson LE,Cabochette P,Germano RFV,Torres D,Boutry S,de Kerchove d'Exaerde A,Bellefroid EJ,Phoenix TN,Devraj K,Lacoste B,Daneman R,Liebner S,Vanhollebeke B, Science. February 18, 2022; 375(6582):1095-9203.
Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., Chandrasekera P,Perfetto M,Lu C,Zhuo M,Bahudhanapati H,Li J,Chen WC,Kulkarni P,Christian L,Liu J,Yien YY,Yu C,Wei S, J Biol Chem. August 1, 2022; 298(8):1083-351X.
Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract., Quaas CE,Lin B,Long DT, J Biol Chem. November 1, 2022; 298(11):1083-351X.
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K,Barak T,Kaulen LD,Henegariu O,Jin SC,Aguilera SM,Yalbir E,Goles G,Nishimura S,Miyagishima D,Djenoune L,Altinok S,Rai DK,Viviano S,Prendergast A,Zerillo C,Ozcan K,Baran B,Sencar L,Goc N,Yarman Y,Ercan-Sencicek AG,Bilguvar K,Lifton RP,Moliterno J,Louvi A,Yuan S,Deniz E,Brueckner M,Gunel M, Proc Natl Acad Sci U S A. April 18, 2023; 120(16):1091-6490.
The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma., Taylor W,Deschamps S,Reboutier D,Paillard L,Méreau A,Audic Y, Cancer Res Commun. December 1, 2022; 2(12):2767-9764.
TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer., Guenther M,Surendran SA,Haas M,Heinemann V,von Bergwelt-Baildon M,Engel J,Werner J,Boeck S,Ormanns S, Br J Cancer. July 1, 2023; 129(1):0007-0920.
ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A,Cousin H,Horr B,Alfandari D,Alfandari D, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.
Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation., Cervino AS,Collodel MG,Lopez IA,Roa C,Hochbaum D,Hukriede NA,Cirio MC, Sci Rep. October 4, 2023; 13(1):2045-2322.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH,Spencer Z,Neitzel LR,Nayak A,Loberg MA,Shen C,Kassel SN,Kroh HK,An Z,Anthony CC,Bryant JM,Lawson A,Goldsmith L,Benchabane H,Hansen AG,Li J,D'Souza S,Lebensohn AM,Rohatgi R,Weiss WA,Weiss VL,Williams C,Hong CC,Robbins DJ,Ahmed Y,Lee E,Lee E, Nat Commun. October 5, 2023; 14(1):2041-1723.
Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology., Sakellakis M,Yoon SM,Reet J,Chalkias A, Channels (Austin). December 1, 2024; 18(1):1933-6969.
Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5., Rinné S,Kiper AK,Jacob R,Ortiz-Bonnin B,Schindler RFR,Fischer S,Komadowski M,De Martino E,Schäfer MK,Cornelius T,Fabritz L,Helker CSM,Brand T,Decher N, iScience. May 17, 2024; 27(5):2589-0042.
Interactions between genistein and Wnt pathway in colon adenocarcinoma and early embryos., Azbazdar Y,Sosa EA,Monka J,Kurmangaliyev YZ,Tejeda-Muñoz N, Heliyon. June 15, 2024; 10(11):.

Kinetic properties of nuclear transport conferred by the retinoblastoma (Rb) NLS., Hu W,Kemp BE,Jans DA, J Cell Biochem. July 1, 2005; 95(4):0730-2312.

AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer., Zhang JS,Gong A,Cheville JC,Smith DI,Young CY, Genes Chromosomes Cancer. July 1, 2005; 43(3):1045-2257.

Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation., Abkevich V,Zharkikh A,Deffenbaugh AM,Frank D,Chen Y,Chen Y,Shattuck D,Skolnick MH,Gutin A,Tavtigian SV, J Med Genet. July 1, 2004; 41(7):1468-6244.

Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome., Grand EK,Grand FH,Chase AJ,Ross FM,Corcoran MM,Oscier DG,Cross NC, Genes Chromosomes Cancer. May 1, 2004; 40(1):1045-2257.

Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E,Du YZ,Mullor JL,Casas E,Allen WP,Gillessen-Kaesbach G,Roeder ER,Ming JE,Ruiz i Altaba A,Muenke M, Proc Natl Acad Sci U S A. November 11, 2003; 100(23):1091-6490.

Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning., Davis RL,Turner DL, Oncogene. December 20, 2001; 20(58):0950-9232.

Notch in vertebrates., Robey E, Curr Opin Genet Dev. August 1, 1997; 7(4):0959-437X.

Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor., Tsutsumi M,Zhou W,Millar RP,Mellon PL,Roberts JL,Flanagan CA,Dong K,Gillo B,Sealfon SC, Mol Endocrinol. July 1, 1992; 6(7):1944-9917.

Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis., Kälin RE,Kretz MP,Meyer AM,Kispert A,Heppner FL,Brändli AW, Dev Biol. May 15, 2007; 305(2):1095-564X.

Non-transcriptional control of DNA replication by c-Myc., Dominguez-Sola D,Ying CY,Grandori C,Ruggiero L,Chen B,Li M,Galloway DA,Gu W,Gautier J,Dalla-Favera R, Nature. July 26, 2007; 448(7152):0143-5221.

The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression., Pittman AM,Naranjo S,Webb E,Broderick P,Lips EH,van Wezel T,Morreau H,Sullivan K,Fielding S,Twiss P,Vijayakrishnan J,Casares F,Qureshi M,Gómez-Skarmeta JL,Houlston RS, Genome Res. June 1, 2009; 19(6):1549-5469.

Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled., Grandy D,Shan J,Zhang X,Rao S,Akunuru S,Li H,Zhang Y,Zhang Y,Alpatov I,Zhang XA,Lang RA,Shi DL,Zheng JJ, J Biol Chem. June 12, 2009; 284(24):1083-351X.

An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis., Kälin RE,Bänziger-Tobler NE,Detmar M,Brändli AW, Blood. July 30, 2009; 114(5):1528-0020.

Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts., Cross MK,Powers MA, Dis Model Mech. January 1, 2009; 2(11-12):1754-8411.

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate., Li Y,Trojer P,Xu CF,Cheung P,Kuo A,Drury WJ,Qiao Q,Neubert TA,Xu RM,Gozani O,Reinberg D, J Biol Chem. December 4, 2009; 284(49):1083-351X.

Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease., Dubaissi E,Papalopulu N, Dis Model Mech. March 1, 2011; 4(2):1754-8411.

Epigenetic reprogramming of breast cancer cells with oocyte extracts., Allegrucci C,Rushton MD,Dixon JE,Sottile V,Shah M,Kumari R,Watson S,Alberio R,Johnson AD, Mol Cancer. January 13, 2011; 10(1):1476-4598.

SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton., Langdon Y,Tandon P,Paden E,Duddy J,Taylor JM,Conlon FL, Development. March 1, 2012; 139(5):1477-9129.

Xenopus as a model system for the study of GOLPH2/GP73 function: Xenopus GOLPH2 is required for pronephros development., Li L,Wen L,Gong Y,Mei G,Liu J,Chen Y,Chen Y,Peng T, PLoS One. January 1, 2012; 7(6):1932-6203.

Isthmin inhibits glioma growth through antiangiogenesis in vivo., Yuan B,Xian R,Ma J,Chen Y,Chen Y,Lin C,Song Y, J Neurooncol. September 1, 2012; 109(2):1573-7373.

Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A,Valensin S,Rossi M,Tunici P,Verani M,De Rosa A,Giordano C,Varrone M,Nencini A,Pratelli C,Benicchi T,Bakker A,Hill J,Sangthongpitag K,Pendharkar V,Liu B,Ng FM,Then SW,Jing Tai S,Cheong SM,He X,Caricasole A,Salerno M, Mol Cancer Ther. July 1, 2013; 12(7):1538-8514.

ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel., Wei X,Sun H,Yan H,Zhang C,Zhang S,Liu X,Hua N,Ma X,Zheng J, Cancer Biol Ther. May 1, 2013; 14(5):1555-8576.

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG,Predes D,Fonseca BF,Cerqueira DM,Reis AH,Dudenhoeffer AC,Borges HL,Mendes FA,Abreu JG, J Biol Chem. December 19, 2014; 289(51):1083-351X.

Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF,Predes D,Cerqueira DM,Reis AH,Amado NG,Cayres MC,Kuster RM,Oliveira FL,Mendes FA,Abreu JG, PLoS One. March 16, 2015; 10(3):1932-6203.

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA,Hardwick LJ,Papkovskaia TD,Thiele CJ,Philpott A, Dis Model Mech. May 1, 2015; 8(5):1754-8411.

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A,Liu B,Liang H,Wei C,Guindani M,Lu Y,Liang S,St John LS,Molldrem J,Nagarajan L, Oncotarget. December 30, 2014; 5(24):1949-2553.

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis., Van Nieuwenhuysen T,Naert T,Tran HT,Van Imschoot G,Geurs S,Sanders E,Creytens D,Van Roy F,Vleminckx K,Vleminckx K, Oncoscience. May 19, 2015; 2(5):2331-4737.

9B.03: A NOVEL INSERTIONAL SOMATIC KCNJ5 MUTATION IN AN AUSTRALIAN PATIENT WITH AN ALDOSTERONE PRODUCING ADENOMA., Xu S,Hardege I,Murthy M,Gordon R,Stowasser M,OʼShaughnessy K, J Hypertens. June 1, 2015; 33 Suppl 1:1473-5598.

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer., Puvirajesinghe TM,Bertucci F,Jain A,Scerbo P,Belotti E,Audebert S,Sebbagh M,Lopez M,Brech A,Finetti P,Charafe-Jauffret E,Chaffanet M,Castellano R,Restouin A,Marchetto S,Collette Y,Gonçalvès A,Macara I,Birnbaum D,Kodjabachian L,Johansen T,Borg JP, Nat Commun. January 12, 2016; 7:2041-1723.

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis., Naert T,Colpaert R,Van Nieuwenhuysen T,Dimitrakopoulou D,Leoen J,Haustraete J,Boel A,Steyaert W,Lepez T,Deforce D,Willaert A,Creytens D,Vleminckx K,Vleminckx K, Sci Rep. October 14, 2016; 6:2045-2322.

TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models., Naert T,Van Nieuwenhuysen T,Vleminckx K,Vleminckx K, Genesis. January 1, 2017; 55(1-2):1526-968X.

Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ,Xie SX,Chen YT,Chen YT,Xue JL,Zhang CJ,Zhu F, World J Gastroenterol. September 7, 2016; 22(33):2219-2840.

TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer., Yan L,Li Q,Yang J,Qiao B, J Cell Biochem. February 1, 2018; 119(2):0730-2312.

Overexpression of TPX2 is associated with progression and prognosis of prostate cancer., Zou J,Huang RY,Jiang FN,Chen DX,Wang C,Wang C,Wang C,Han ZD,Liang YX,Zhong WD, Oncol Lett. September 1, 2018; 16(3):1792-1074.

CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs., Naert T,Vleminckx K,Vleminckx K, Drug Discov Today Technol. August 1, 2018; 28:1740-6749.

TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z,Zheng B,Li J,Lv X,Zhang H,Yu F,Kong L,Li Y,Yu M,Fang L,Liang B, Biomed Pharmacother. November 1, 2018; 107:0753-3322.

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R, Biochem Biophys Res Commun. December 9, 2018; 507(1-4):1090-2104.

Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer., Dimitrakopoulou D,Tulkens D,Van Vlierberghe P,Vleminckx K,Vleminckx K, Front Physiol. January 1, 2019; 10:1664-042X.

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer., Daulat AM,Finetti P,Revinski D,Silveira Wagner M,Camoin L,Audebert S,Birnbaum D,Kodjabachian L,Borg JP,Bertucci F, Br J Cancer. April 1, 2019; 120(9):0007-0920.

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Chen M,Neul C,Schaeffeler E,Frisch F,Winter S,Schwab M,Koepsell H,Hu S,Laufer S,Baker SD,Sparreboom A,Nies AT, Clin Pharmacol Ther. January 1, 2020; 107(1):1532-6535.

Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P,Kujawa KA,Cortez AJ,Lisowska KM, Diagnostics (Basel). September 14, 2019; 9(3):2075-4418.

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN,Aguero TH,Owens DA,Kurtenbach S,Field MG,Durante MA,Rodriguez DA,King ML,Harbour JW, Sci Adv. September 18, 2019; 5(9):2375-2548.

Identification of Drivers of Aneuploidy in Breast Tumors., Pfister K,Pipka JL,Chiang C,Liu Y,Clark RA,Keller R,Skoglund P,Guertin MJ,Hall IM,Stukenberg PT, Cell Rep. May 29, 2018; 23(9):2211-1247.

RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis., Naert T,Dimitrakopoulou D,Tulkens D,Demuynck S,Carron M,Noelanders R,Eeckhout L,Van Isterdael G,Deforce D,Vanhove C,Van Dorpe J,Creytens D,Vleminckx K,Vleminckx K, Oncogene. March 1, 2020; 39(13):0950-9232.

Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning., Reis AH,Sokol SY, Development. May 27, 2020; 147(10):1477-9129.

Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors., Prevost MS,Bouchenaki H,Barilone N,Gielen M,Corringer PJ, Cell Mol Life Sci. February 1, 2021; 78(3):1420-9071.

Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M,Shulepko M,Osmakov D,Andreev Y,Sudarikova A,Vasileva V,Pavlyukov MS,Latyshev YA,Potapov AA,Kirpichnikov M,Shenkarev ZO,Lyukmanova E, Cancers (Basel). July 8, 2020; 12(7):2072-6694.

Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma., Kuznetsoff JN,Owens DA,Lopez A,Rodriguez DA,Chee NT,Kurtenbach S,Bilbao D,Roberts ER,Volmar CH,Wahlestedt C,Brothers SP,Harbour JW, Mol Cancer Res. February 1, 2021; 19(2):1557-3125.

Allosteric regulation of mammalian Na+/I- symporter activity by perchlorate., Llorente-Esteban A,Manville RW,Reyna-Neyra A,Abbott GW,Amzel LM,Carrasco N, Nat Struct Mol Biol. June 1, 2020; 27(6):1545-9985.

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.

Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P, Genesis. February 1, 2021; 59(1-2):1526-968X.

Use of Xenopus laevis cell-free extracts to study BRCA2 role in chromosome alignment., El Dika M, DNA Repair (Amst). April 1, 2021; 100:1568-7856.

BRCA1-BARD1 regulates transcription through BRD4 in Xenopus nucleoplasmic extract., Barrows JK,Fullbright G,Long DT, Nucleic Acids Res. April 6, 2021; 49(6):1362-4962.

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability., Matson DR,Denu RA,Zasadil LM,Burkard ME,Weaver BA,Flynn C,Stukenberg PT, BMC Cancer. February 23, 2021; 21(1):1471-2407.

Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus., Moreno MM,Barrell WB,Godwin A,Guille M,Liu KJ,Liu KJ, Gene Expr Patterns. June 1, 2021; 40:1567-133X.

Modeling endoderm development and disease in Xenopus., Edwards NA,Zorn AM, Curr Top Dev Biol. January 1, 2021; 145:1557-8933.

Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide., Fuchs RP,Isogawa A,Paulo JA,Onizuka K,Takahashi T,Amunugama R,Duxin JP,Fujii S, Elife. July 8, 2021; 10:2050-084X.

Weight of Evidence and Human Relevance Evaluation of the Benfluralin Mode of Action in Rats (Part II): Thyroid carcinogenesis., Strupp C,Quesnot N,Weber-Parmentier C,Richert L,Bomann WH,Singh P, Regul Toxicol Pharmacol. November 1, 2020; 117:1096-0295.

Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells., Okuno H,Okano H, Regen Ther. August 24, 2021; 18:2352-3204.

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H,Lee H,Sun R,Niehrs C, J Biol Chem. February 1, 2022; 298(2):1083-351X.

Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders., Martin M,Vermeiren S,Bostaille N,Eubelen M,Spitzer D,Vermeersch M,Profaci CP,Pozuelo E,Toussay X,Raman-Nair J,Tebabi P,America M,De Groote A,Sanderson LE,Cabochette P,Germano RFV,Torres D,Boutry S,de Kerchove d'Exaerde A,Bellefroid EJ,Phoenix TN,Devraj K,Lacoste B,Daneman R,Liebner S,Vanhollebeke B, Science. February 18, 2022; 375(6582):1095-9203.

Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., Chandrasekera P,Perfetto M,Lu C,Zhuo M,Bahudhanapati H,Li J,Chen WC,Kulkarni P,Christian L,Liu J,Yien YY,Yu C,Wei S, J Biol Chem. August 1, 2022; 298(8):1083-351X.

Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract., Quaas CE,Lin B,Long DT, J Biol Chem. November 1, 2022; 298(11):1083-351X.

Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K,Barak T,Kaulen LD,Henegariu O,Jin SC,Aguilera SM,Yalbir E,Goles G,Nishimura S,Miyagishima D,Djenoune L,Altinok S,Rai DK,Viviano S,Prendergast A,Zerillo C,Ozcan K,Baran B,Sencar L,Goc N,Yarman Y,Ercan-Sencicek AG,Bilguvar K,Lifton RP,Moliterno J,Louvi A,Yuan S,Deniz E,Brueckner M,Gunel M, Proc Natl Acad Sci U S A. April 18, 2023; 120(16):1091-6490.

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma., Taylor W,Deschamps S,Reboutier D,Paillard L,Méreau A,Audic Y, Cancer Res Commun. December 1, 2022; 2(12):2767-9764.

TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer., Guenther M,Surendran SA,Haas M,Heinemann V,von Bergwelt-Baildon M,Engel J,Werner J,Boeck S,Ormanns S, Br J Cancer. July 1, 2023; 129(1):0007-0920.

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A,Cousin H,Horr B,Alfandari D,Alfandari D, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation., Cervino AS,Collodel MG,Lopez IA,Roa C,Hochbaum D,Hukriede NA,Cirio MC, Sci Rep. October 4, 2023; 13(1):2045-2322.

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH,Spencer Z,Neitzel LR,Nayak A,Loberg MA,Shen C,Kassel SN,Kroh HK,An Z,Anthony CC,Bryant JM,Lawson A,Goldsmith L,Benchabane H,Hansen AG,Li J,D'Souza S,Lebensohn AM,Rohatgi R,Weiss WA,Weiss VL,Williams C,Hong CC,Robbins DJ,Ahmed Y,Lee E,Lee E, Nat Commun. October 5, 2023; 14(1):2041-1723.

Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology., Sakellakis M,Yoon SM,Reet J,Chalkias A, Channels (Austin). December 1, 2024; 18(1):1933-6969.

Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5., Rinné S,Kiper AK,Jacob R,Ortiz-Bonnin B,Schindler RFR,Fischer S,Komadowski M,De Martino E,Schäfer MK,Cornelius T,Fabritz L,Helker CSM,Brand T,Decher N, iScience. May 17, 2024; 27(5):2589-0042.

Interactions between genistein and Wnt pathway in colon adenocarcinoma and early embryos., Azbazdar Y,Sosa EA,Monka J,Kurmangaliyev YZ,Tejeda-Muñoz N, Heliyon. June 15, 2024; 10(11):.