The rel protein is a transcription factor of the nf-κb family and functions as a subunit of the nf-κb complex, which regulates gene expression involved in immune and inflammatory responses; it is local...[+]

The rel protein is a transcription factor of the nf-κb family and functions as a subunit of the nf-κb complex, which regulates gene expression involved in immune and inflammatory responses; it is localized to the cytoplasm in an inactive state bound to iκb inhibitors and translocates to the nucleus upon activation. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD