The hcrt gene encodes a neuropeptide precursor protein producing hypocretin/orexin peptides, which are signaling molecules involved in the regulation of feeding behavior and sleep-wake cycles. In situ ...[+]

The hcrt gene encodes a neuropeptide precursor protein producing hypocretin/orexin peptides, which are signaling molecules involved in the regulation of feeding behavior and sleep-wake cycles. In situ hybridization shows hcrt expression is localized within neurons of the posterior hypothalamic area. The synthesized preprohormone is processed into secreted peptide neurotransmitters. [-]

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