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Summary Expression Phenotypes Gene Literature (59) GO Terms (26) Nucleotides (47) Proteins (31) Interactants (579) Wiki
XB-GENEPAGE-957719
???displayGene.symbol???:
 itk

???displayGene.name???: 
IL2-inducible T cell kinase

???displayGene.synonyms???
emt , lyk , psctk2 ( Nomenclature history )

???displayGene.geneFunction???
Tyrosine kinases

AI Protein Function :
The itk gene encodes a Tec family tyrosine kinase expressed in the thymus and spleen. The itk protein functions as an intracellular signaling molecule involved in T-cell receptor signaling pathways, in...[+]


InterPro :
Kinase-like dom sf, Non-receptor tyrosine kinases, PH-like dom sf, PH domain, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
lymphoproliferative syndrome 1

MIM:
LYMPHOPROLIFERATIVE SYNDROME 1; LPFS1

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info