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2020 Xenopus White Paper

Dear Xenopus Community,

The 2020 Xenopus Community White Paper is finished and was prepared by:

John Wallingford (University of Texas at Austin)
Marko Horb (National Xenopus Resource, Marine Biological Laboratory)
Aaron Zorn (Xenbase, Cincinnati Children’s Hospital)
Leonid Peshkin (Harvard Medical School)
Mustafa Khokha (Yale Medical School)


Table of contents for the 2020 Xenopus White Paper: 

I. Executive summary

    A. Xenopus is an essential vertebrate model system for biomedical research
    B. The NIH has made a substantial recent investment in biomedical research using Xenopus
    C. The NIH investment in Xenopus has been well justified by discoveries in basic biology
    D. NIH investment in Xenopus has led to significant advances in understanding human disease
    E. There is a broad consensus among the Xenopus community regarding our most pressing infrastructure needs
    F. The Xenopus community has identified two Immediate Needs and one Essential Resource

II: Consensus building process for the 2020 Xenopus White Paper

III: The Immediate Needs identified by the Xenopus Community

    A. Renewal of Xenbase
    B. Enhancement of efficient gene editing approaches and mutant lines

IV: An Essential Resource needed by the Xenopus Community 

    XenCAt: A single cell atlas of Xenopus development

V: General Conclusion

VI: Appendices

    A. Authors of the 2020 Xenopus White Paper
    B. The Cold Spring Harbor Laboratory Course on “Cell and Developmental Biology of Xenopus.”
    C. The International Xenopus Conference
    D. The Xenopus Resources and Emerging Technologies (XRET) Meeting


Download the 2020 Xenopus Community White Paper:

     Word Document



PIs: Please reference the White Paper in your NIH grant proposals and contact your program officers.

Last Updated: 2020-02-05