Xenbase Image ID: 130835

Fig. 9. Temporal and spatial expression of TMEFF1 during early Xenopus development. (A) TMEFF1 is expressed from midgastrula stages onward. (B) At gastrula stages (stage 11–11.5), TMEFF1 is expressed mainly in ectodermal tissues (animal), weakly in the marginal zone (DMZ and VMZ, dorsal and ventral marginal zone, respectively), and is absent from the vegetal region. (C) Spatial expression of TMEFF1. (a) TMEFF1 is expressed in the neural plate at early neurula stages. The embryo is viewed from the dorsal side. (b–d) As neurulation proceeds, TMEFF1 expression is enriched in the neural folds and in the dorsal neural tube (b and d, dorsal view; c, lateral view). (e, f) At tailbud stages, TMEFF1 is detected in the diencephalon, midbrain, hindbrain, otic vesicles, cranial nerve placodes, and the trunk dorsal neural tissue. di, diencephalon; mb, midbrain; hb, hindbrain; nt(d), neural tube (dorsal); ot, otic vesicle; pl, cranial nerve placodes. The embryo is viewed laterally ( e) and dorsolaterally (f). Image published in: Chang C et al. (2003) Copyright © 2003. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue tmeff1.S tomoregulin-1, X7365 X. laevis Throughout NF stage 14 anterior neural fold neural plate pre-chordal neural plate tmeff1.S tomoregulin-1, X7365 X. laevis Sometime during NF stage 16 to NF stage 18 neural plate pre-chordal neural plate chordal neural plate trigeminal placode profundal placode tmeff1.S tomoregulin-1, X7365 X. laevis Throughout NF stage 26 to NF stage 28 otic vesicle brain midbrain hindbrain neural tube posterior neural tube spinal cord diencephalon cranial placode Image source: Published Larger Image Printer Friendly View

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