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XB-PHENO-27147

Xla Wt + ctnnb1 MO, Azbazdar Y and De Robertis EM (2024)

Experiment + Assay: Xla Wt + ctnnb1 MO + NF13 (RT-PCR)
Background: Xla.B strain x J strain
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection ctnnb1 MO1 ctnnb1
 NF stage 3 (4-cell) left-ventral blastomere
morpholino injection ctnnb1 MO1 ctnnb1
 NF stage 3 (4-cell) right-ventral blastomere
Conditions:
Assay Type Assay Stages Antibody
RT-PCR NF stage 13  
Expression Phenotypes (3):
decreased amount ncam1.L expression in neural plate
absent otx2.L expression in dorsal marginal zone
absent rax.L expression in eye primordium
Source: Fig. S3 GHI
Article: XB-ART-60778, PubMed