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XB-PHENO-27092

Xla Wt + fbrsl1 MO (sb), Berger H et al. (2024)

Experiment + Assay: Xla Wt + fbrsl1 MO (sb) + NF44 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection fbrsl1 MO1 fbrsl1 (Xla)
 NF stage 3 (4-cell) left-dorsal blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 44  
Anatomical Phenotypes: abnormal heart morphology
Expression Phenotypes (2):
absent myh6.L expression in heart
decreased amount myh6.L expression in musculature of face
Human Disease Associations: congenital heart disease
Source: Fig. 2 C
Article: XB-ART-60633, PubMed