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XB-PHENO-26920

Xla Wt + folr1 MO, Balashova OA et al. (2024)

Experiment + Assay: Xla Wt + folr1 MO + NF15-17 (immunohistochemistry)
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection folr1 MO1 folr1 (Xla)
NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 15 to NF stage 17  
Anatomical Phenotypes: abnormal apical constriction
Expression Phenotypes (1):
increased amount eea1.L expression in neural plate
Human Disease Associations: neural tube defect
Source: Fig. 4 f
Article: XB-ART-60607, PubMed