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XB-PHENO-26283

Xla Wt + nppa MO, Devotta A et al. (2023)

Experiment + Assay: Xla Wt + nppa MO + NF15 (in situ hybridization)
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection nppa MO1 nppa (Xla)
 NF stage 2 (2-cell) animal pole
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 15  
Expression Phenotypes (4):
decreased amount six1.L expression in anterior placodal area
decreased amount snai2.L expression in neural crest
absent sox10.L expression in cranial neural crest
increased amount sox2.L expression in neural plate
Source: Fig 6 Ar1 B
Article: XB-ART-59841, PubMed