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XB-PHENO-25864

Xla Wt + adam11 MO + cnc explant + fibronectin, Pandey A et al. (2023)

Experiment + Assay: Xla Wt + adam11 MO + cnc explant + fibronectin + NF18 (immunohistochemistry)
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection adam11 MO1 adam11 (Xla)
 NF stage 2 (2-cell) animal blastomere
peptide/protein fn1 fn1 (Xla)
 NF stage 17 anatomical entity in vitro
explant  
NF stage 17 cranial neural crest
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 18  
Anatomical Phenotypes: increased cell population proliferation
Expression Phenotypes (2):
increased amount ccnd1.L expression in cranial neural crest
increased amount ctnnb1.L expression in cranial neural crest
Source: Fig. 4. A-E
Article: XB-ART-60305, PubMed