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XB-PHENO-25434

Xtr Wt + sox17a MO + sox17b.1/b.2 MO, Mukherjee S et al. (2020)

Experiment + Assay: Xtr Wt + sox17a MO + sox17b.1/b.2 MO + NF10.5 (in situ hybridization)
Background: Xtr.NigerianNasco
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection sox17b.1/b.2 MO1 sox17b.2
sox17b.1
 NF stage 2- blastomere
morpholino injection sox17a MO5 sox17a
 NF stage 2- blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 10.5  
Expression Phenotypes (9):
increased amount dkk1 expression in central endoderm
increased amount dkk1 expression in endomesoderm
decreased amount foxa1 expression in endoderm
decreased amount foxa1 expression in ventral marginal zone
increased amount lhx5 expression in endoderm
decreased amount osr1 expression in endoderm
decreased amount osr1 expression in endomesoderm
decreased amount six1 expression in dorsal endoderm
decreased amount six1 expression in dorsal endomesoderm
Source: Fig.5.Col.2
Article: XB-ART-57340, PubMed