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Summary Expression Phenotypes Gene Literature (21) GO Terms (10) Nucleotides (81) Proteins (40) Interactants (471) Wiki
XB-GENEPAGE-946234
???displayGene.symbol???:
 rspo2

???displayGene.name???: 
R-spondin 2

???displayGene.synonyms???
CRISTIN2 , R-spondin 2 ( Nomenclature history )

???displayGene.geneFunction???
Subtilisin-like proprotein convertase

Protein Function :
Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors. Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptor...[+]


InterPro :
PDEase catalytic dom, PDEase N, PDEase CS, PDEase, [+]

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Diseases: 


Disease Ontology:
tetraamelia syndrome 2

External Links:
1/4
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info