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Summary Expression Phenotypes Gene Literature (42) GO Terms (11) Nucleotides (122) Proteins (47) Interactants (248) Wiki
XB-GENEPAGE-943035
???displayGene.symbol???:
 nbn

???displayGene.name???: 
nibrin

???displayGene.synonyms???
nbs , nbs1 , nibrin ( Nomenclature history )

???displayGene.geneFunction???
Transcription initiation factor IIF, large subunit (RAP74)

Protein Function :
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand b...[+]


InterPro :
SMAD FHA dom sf, Nibrin met, BRCT dom sf, Nibrin BRCT2, [+]

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Diseases: 


Disease Ontology:
aplastic anemia [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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