XB-IMG-82818
Xenbase Image ID: 82818
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Fig. 7. The site of LLT generation coincides with low pFAK immunoreactivity.
(A) Fluo-4 fluorescence image of a growth cone generating an LLT (arrow). (B)
pFAK immunoreactivity of the same cell 5 min following the incidence of the
LLT shows reduced staining in the region of the growth cone where the LLT
occurred (yellow dashed circle). This result was observed in 6 of 6 neuronal
growth cones that were fixed and stained for pFAK following the observation
of an LLT during Ca2+ imaging. (C) Fluo-4 image of a growth cone not
generating an LLT during the period of imaging. (D) There are no regions of
distinctively low intensity pFAK immunoreactivity in the growth cone. Results
similar to panels C and D were obtained from 6 of 6 growth cones. Image published in: Conklin MW et al. (2005) Copyright © 2005. Image reproduced with permission of the Publisher, Elsevier B. V.
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