Xenbase Image ID: 171569

Fig. 4. Spatial expression pattern of adgra2 mRNA during Xenopus laevis embryogenesis. Spatial expression pattern of adgra2 is visualized by WMISH. Embryonic stages are indicated in each panel. a-c. Lateral views with animal to the top. d-f. Anterior views with dorsal to the top. g-j. Lateral views with anterior to the left. f, g. The first tissue specific adgra2 expression starts at stage 23 in the periocular mesenchyme (POM), the migrating neural crest cells (NCC) and the intersomitic arteries (IA). h. At stage 25, adgra2 is expressed in the periocular mesenchyme (POM), the migrating cranial neural crest cells (NCC) and the intersomitic arteries (IA). i. At stage 30, adgra2 was detected in the branchial (BA), hyoidal (HA) and mandibular (MA) arches, the periocular mesenchyme (POM), the intersomitic arteries (IA) and the posterior cardinal vein (PCV). j. At stage 35 adrga2 transcripts were detected in the pharyngeal arches (BA, HA and MA), in the intersomitic arteries (IA), the vascular system (VS), the posterior cardinal vein (PCV) and the proctodeum (PD). a, animal; A, anterior; BA, branchial arches; BP, blastoporus; D, dorsal; HA, hyoidal arch; IA, intersomitic arteries; MA, mandibular arch; NCC, neural crest cells; P, posterior; PCV, posterior cardinal vein; PD, proctodeum; POM, periocular mesenchyme; v, vegetal; V, ventral. Scale bars: 500 μm (a–h): 1 mm (i, j). Image published in: Seigfried FA et al. (2018) Copyright © 2018. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue adgra2.L gpr124, LOC108712783, tem5 X. laevis Sometime during NF stage 1 to NF stage 20 adgra2.L gpr124, LOC108712783, tem5 X. laevis Sometime during NF stage 23 to NF stage 25 periocular region head mesenchyme migratory neural crest cell adgra2.L gpr124, LOC108712783, tem5 X. laevis Throughout NF stage 29 and 30 mandibular arch hyoid arch branchial arch intersomitic artery posterior cardinal vein periocular region head mesenchyme myocardium circulatory system intersomitic vessel vascular plexus adgra2.L gpr124, LOC108712783, tem5 X. laevis Throughout NF stage 33 and 34 pharyngeal arch mandibular arch intersomitic artery posterior cardinal vein periocular region head mesenchyme heart myocardium secondary heart field pericardium pericardial roof endocardium optic vesicle adgra2.L gpr124, LOC108712783, tem5 X. laevis Throughout NF stage 35 and 36 pharyngeal arch mandibular arch hyoid arch branchial arch intersomitic artery posterior cardinal vein proctodeum neural crest heart optic vesicle circulatory system vascular plexus Image source: Published Larger Image Printer Friendly View

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