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Fig. S5. Expression analysis of Insulin/Insulin-like growth factor (Igf) signaling. Whole-mount in situ hybridizations and paraplast sections thereof comparing igf1 (A–B′′), igf3 (C–D′′), insulin receptor (insr) (E–F′′), insulin receptor substrate 1 (G–H′′), igf2 (I), insulin (ins) (K), igf receptor (igfr) (M), and insulin-related receptor (insrr) (N) at stages 34 (A, C, E, G, I, and K) and 38 (B–B′′, D–D′′, F–F′′, H–H′′, M, and N). (J and L) In situ hybridizations on paraplast sections of stage 42 Xenopus embryos for igf2 and insulin. Insets show sense control.