mecom has 4 expression phenotype(s)
Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. 2. A e-h

Buisson I et al. (2015)
Xla Wt + pax2 MO

NF33/34-35/36 (in situ hybridization)
Expression Phenotype
absent mecom.L expression in proximal tubule
absent cimap1a.L expression in pronephric nephrostome
decreased amount rgn.L expression in proximal tubule
increased amount pax2.L expression in proximal tubule
Sup.Fig. S2 A a-k

Buisson I et al. (2015)
Xla Wt + pax2 MO3

NF33/34-35/36 (in situ hybridization)
Expression Phenotype
decreased amount mecom.L expression in proximal tubule
absent clcnkb.L expression in pronephric duct
absent clcnkb.L expression in pronephric kidney
decreased amount atp1b1.S expression in proximal tubule
decreased amount cimap1a.L expression in pronephric nephrostome
decreased amount cldn19.L expression in proximal tubule
decreased amount pax2.L expression in proximal tubule
decreased amount rgn.L expression in glomus
decreased amount slc12a1.L expression in proximal tubule
Fig. 3A a-e

Buisson I et al. (2015)
Xla Wt + pax8 MO

NF25 (in situ hybridization)
Expression Phenotype
decreased amount mecom.L expression in pronephric mesenchyme
absent hnf1b.L expression in pronephric mesenchyme
absent lhx1.L expression in pronephric mesenchyme
absent pax2.L expression in pronephric mesenchyme
Fig. 2. A a-d

Buisson I et al. (2015)
Xla Wt + pax8 MO

NF33/34-35/36 (in situ hybridization)
Anatomical Phenotype
abnormal pronephric kidney morphology
absent pronephric tubule
Expression Phenotype
absent mecom.L expression in distal tubule
absent mecom.L expression in early distal tubule
absent mecom.L expression in pronephric duct
absent cimap1a.L expression in pronephric nephrostome
absent pax2.L expression in pronephric duct
absent pax2.L expression in pronephric kidney
absent pax2.L expression in pronephric nephrostome
absent pax2.L expression in pronephric tubule
absent rgn.L expression in pronephric tubule