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Xla Wt + pax2 MO, Buisson I et al. (2015)

Experiment + Assay: Xla Wt + pax2 MO + NF33/34-35/36 (in situ hybridization)
Background: Xla.Outbred
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pax2 MO2 pax2.L
NF stage 4 (8-cell) blastomere
Assay Type Assay Stages Antibody
in situ hybridization NF stage 33 and 34 to NF stage 35 and 36  
Expression Phenotypes (4):
absent cimap1a.L expression in pronephric nephrostome
absent mecom.L expression in proximal tubule
increased amount pax2.L expression in proximal tubule
decreased amount rgn.L expression in proximal tubule
Source: Fig. 2. A e-h
Article: XB-ART-49971, PubMed