en2 has 19 expression phenotype(s)
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Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. 5 H

Patel JH et al. (2022)
Xtr.Tg(pbin7:GFP) + hif1a MO

NF18 (in situ hybridization)
Anatomical Phenotype
abnormal neural plate morphology
abnormal Wnt signaling pathway
Expression Phenotype
mislocalised en2 expression in hindbrain
mislocalised otx2 expression in forebrain
Fig.6.S1.E

Chen M et al. (2020)
Xla Wt + tmem79 MO

NF16 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in presumptive midbrain-hindbrain boundary
decreased amount ag1.L expression in anterior neural ridge
decreased amount ag1.L expression in cement gland primordium
decreased amount egr2.L expression in rhombomere R3
decreased amount egr2.L expression in rhombomere R5
decreased amount foxg1.L expression in anterior neural ridge
decreased amount tubb2b.L expression in neural plate
decreased amount tubb2b.L expression in Rohon-Beard neuron
decreased amount tubb2b.L expression in trigeminal placode
Fig 2. E

Kirsch N et al. (2017)
Xla Wt + angptl4

NF18 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in midbrain-hindbrain boundary
Fig 2. E

Kirsch N et al. (2017)
Xla Wt + lrp6 MO

NF18 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in midbrain-hindbrain boundary
fig.4.b

Zhao Y et al. (2016)
Xla Wt + efhc1 MO

NF18 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in presumptive midbrain-hindbrain boundary
fig.2.c

Miyagi A et al. (2015)
Xla Wt + flop2 MO

NF17-18 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in presumptive midbrain-hindbrain boundary
decreased amount foxg1.L expression in anterior neural ridge
fig.2.c

Miyagi A et al. (2015)
Xla Wt + flop2 MO + mgc69520 MO

NF17-18 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in presumptive midbrain-hindbrain boundary
decreased amount foxg1.L expression in anterior neural ridge
fig.2.c

Miyagi A et al. (2015)
Xla Wt + mgc69520 MO

NF17-18 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in presumptive midbrain-hindbrain boundary
decreased amount foxg1.L expression in anterior neural ridge
fig.3.e

Zhu X et al. (2015)
Xla Wt + Nf2 MO

NF23-24 (in situ hybridization)
Expression Phenotype
mislocalised en2.L expression in presumptive midbrain-hindbrain boundary
decreased amount rax.L expression in retinal neural layer
mislocalised egr2.L expression in hindbrain
fig.3.A.n,o

Pfirrmann T et al. (2015)
Xla Wt + rmnd5a MO

NF35/36-35 and 36 (in situ hybridization)
Expression Phenotype
decreased amount en2.L expression in hindbrain