Fig. S3 E

Azbazdar Y and De Robertis EM (2024)

Xla Wt + ctnnb1 MO

NF10.5 (in situ hybridization)

Expression Phenotype
absent otx2.L expression in dorsal marginal zone

Fig. S3 GHI

Azbazdar Y and De Robertis EM (2024)

Xla Wt + ctnnb1 MO

NF13 (RT-PCR)

Expression Phenotype
absent otx2.L expression in dorsal marginal zone absent rax.L expression in eye primordium decreased amount ncam1.L expression in neural plate

Fig. 3. B

Eroshkin FM et al. (2024)

Xla Wt + neurectoderm explant + stretch

NF14 (RT-PCR)

Expression Phenotype

decreased amount otx2.L expression in neuroectoderm
decreased amount cd82.L expression in neuroectoderm
decreased amount cebpa.L expression in neuroectoderm
decreased amount gsc.L expression in neuroectoderm
decreased amount six3.L expression in neuroectoderm
increased amount cdx4.L expression in neuroectoderm
increased amount tbxt.L expression in neuroectoderm
increased amount xmc.L expression in neuroectoderm

Fig. 5 H

Patel JH et al. (2022)

Xtr.Tg(pbin7:GFP) + hif1a MO

NF18 (in situ hybridization)

Anatomical Phenotype
abnormal neural plate morphology abnormal Wnt signaling pathway

Expression Phenotype
mislocalised otx2 expression in forebrain mislocalised en2 expression in hindbrain

Fig.7.C

Gur M et al. (2022)

Xla Wt + aldh1a2 CRISPR

NF12 (RT-PCR)

Expression Phenotype
decreased amount otx2.L expression in embryo decreased amount aldh1a2.L expression in the embryo decreased amount cer1.L expression in embryo decreased amount chrd.1.L expression in the embryo decreased amount hoxa1.L expression in embryo decreased amount hoxb4.L expression in embryo

Fig.7.B

Gur M et al. (2022)

Xla Wt + aldh1a3 CRISPR

NF10.25 (RT-PCR)

Expression Phenotype
increased amount otx2.L expression in embryo decreased amount admp.L expression in the embryo decreased amount chrd.1.L expression in the embryo decreased amount cyp26a1.L expression in the embryo decreased amount frzb.L expression in the embryo decreased amount hoxb4.L expression in embryo

Fig.3.A-G

Gur M et al. (2022)

Xla Wt + DEAB

NF10.25 (RT-PCR)

Expression Phenotype
decreased amount otx2.L expression in embryo decreased amount admp.L expression in the embryo decreased amount cer1.L expression in embryo decreased amount chrd.1.L expression in the embryo decreased amount cyp26a1.L expression in the embryo decreased amount dkk1.L expression in embryo decreased amount hoxb1.L expression in embryo

Fig.1.H

Gur M et al. (2022)

Xla Wt + DEAB

NF10.25 (RT-PCR)

Expression Phenotype
decreased amount otx2.L expression in embryo decreased amount admp.L expression in the embryo decreased amount cer1.L expression in embryo decreased amount cyp26a1.L expression in the embryo

Fig.3.A-G

Gur M et al. (2022)

Xla Wt + Retinoic acid

NF10.25 (RT-PCR)

Expression Phenotype
decreased amount otx2.L expression in embryo decreased amount admp.L expression in the embryo decreased amount cer1.L expression in embryo decreased amount chrd.1.L expression in the embryo decreased amount dkk1.L expression in embryo decreased amount muc2.L expression in cement gland increased amount cyp26a1.L expression in the embryo increased amount hoxb1.L expression in embryo

Fig.1.S1.D

Mukherjee S et al. (2020)

Xtr Wt + sox17a MO + sox17b.1/b.2 MO

NF10.5 (in situ hybridization)

Expression Phenotype

decreased amount otx2 expression in dorsal endomesoderm
decreased amount otx2 expression in dorsal involuting marginal zone
decreased amount admp expression in dorsal involuting marginal zone
decreased amount dhh expression in blastopore lip
decreased amount gata4 expression in endoderm
increased amount wnt8a expression in the animal cap
increased amount nodal1 expression in endoderm
increased amount nodal1 expression in marginal zone
increased amount nodal1 expression in ventral marginal zone
increased amount wnt8a expression in blastocoel floor
increased amount wnt8a expression in ectoderm
increased amount wnt8a expression in ventral marginal zone