Fig. 5 C D

Yuan L et al. (2014)

Xla Wt + ern1 MO

NF 30

Expression Phenotype
decreased amount ptf1a.L expression in anterior endoderm decreased amount ptf1a.L expression in pancreas decreased amount pdx1.L expression in anterior endoderm decreased amount pdx1.L expression in pancreas

fig.3.a,c

Shifley ET et al. (2012)

Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + B/B Homodimerizer

NF35/36 (in situ hybridization)

Expression Phenotype
decreased amount ptf1a.S expression in dorsal pancreatic bud decreased amount ptf1a.S expression in ventral pancreatic bud decreased amount pdx1.L expression in dorsal pancreatic bud decreased amount pdx1.L expression in ventral pancreatic bud increased amount hhex.L expression in liver increased amount nkx2-1.L expression in lung bud increased amount nr1h5.L expression in liver

Fig 3

Shifley ET et al. (2012)

Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + B/B Homodimerizer

NF37/38 (in situ hybridization)

Expression Phenotype

decreased amount ptf1a.S expression in pancreas
decreased amount pdx1.L expression in pancreas
decreased amount spry2.L expression in eye
increased amount hhex.L expression in liver primordium
increased amount nkx2-1.L expression in lung bud
increased amount nr1h5.L expression in liver primordium
mislocalised nkx2-1.L expression in lung bud
mislocalised nr1h5.L expression in liver primordium

Fig.1.C

McLin VA et al. (2007)

Xla Wt + gsk3b

NF42 (in situ hybridization)

Expression Phenotype
mislocalised ptf1a.S expression in intestine mislocalised ambp.L expression in intestine mislocalised cela1.2.L expression in intestine mislocalised nr1h5.L expression in intestine

fig.S4.2

Afelik S et al. (2006)

Xla Wt + pdx1 MO

NF41 (in situ hybridization)

Anatomical Phenotype
abnormal dorsal fin margin morphology abnormal ventral fin margin morphology

Expression Phenotype
decreased amount ptf1a.S expression in dorsal pancreatic bud decreased amount ptf1a.S expression in ventral pancreatic bud

fig.S4.3

Afelik S et al. (2006)

Xla Wt + pdx1 MO + ptf1a MO

NF41 (in situ hybridization)

Anatomical Phenotype
abnormal bending of tail

Expression Phenotype
decreased amount ptf1a.S expression in dorsal pancreatic bud decreased amount ptf1a.S expression in ventral pancreatic bud

fig.S3.2

Afelik S et al. (2006)

Xla Wt + ptf1a MO

NF41 (in situ hybridization)

Expression Phenotype
decreased amount ptf1a.S expression in dorsal pancreatic bud decreased amount ptf1a.S expression in ventral pancreatic bud

fig.S5.4

Afelik S et al. (2006)

Xla Wt + ptf1a MO

NF41 (in situ hybridization)

Expression Phenotype
mislocalised ptf1a.S expression in foregut