six1 has 41 expression phenotype(s)
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Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. 3 (gastrula)

Damuth DL et al. (2024)
Xla Wt + Xla.sox21.L

NF11-11.5 (RT-PCR)
Expression Phenotype
increased amount six1.L expression in preplacodal ectoderm
increased amount myt1.L expression in neural stem cell
Fig. 3 (neurula)

Damuth DL et al. (2024)
Xla Wt + Xla.sox21.S

NF15 (RT-PCR)
Expression Phenotype
increased amount six1.L expression in preplacodal ectoderm
decreased amount sox2.L expression in neural stem cell
decreased amount tubb2b.L expression in neuron
increased amount myt1.L expression in neural stem cell
increased amount neurod1.L expression in neural progenitor cell
Fig. 5 FG

Devotta A et al. (2023)
Xla wt + A71915 (npr1 antagonist)

NF15 (in situ hybridization)
Expression Phenotype
decreased amount six1.L expression in anterior placodal area
decreased amount snai2.L expression in neural crest
Fig 2 FG

Devotta A et al. (2023)
Xla wt + AP-811 (npr3 antagonist)

NF15 (in situ hybridization)
Expression Phenotype
absent six1.L expression in anterior placodal area
Fig 6 Ar1 B

Devotta A et al. (2023)
Xla Wt + nppa MO

NF15 (in situ hybridization)
Expression Phenotype
decreased amount six1.L expression in anterior placodal area
absent sox10.L expression in cranial neural crest
decreased amount snai2.L expression in neural crest
increased amount sox2.L expression in neural plate
Fig 6 A:r3 BDE

Devotta A et al. (2023)
Xla Wt + nppc MO

NF15 (in situ hybridization)
Expression Phenotype
absent six1.L expression in anterior placodal area
absent sox10.L expression in cranial neural crest
decreased amount snai2.L expression in neural crest
increased amount sox2.L expression in neural plate
Fig. 5 B:c2r1 CD

Devotta A et al. (2023)
Xla Wt + npr1 MO

NF15 (in situ hybridization)
Expression Phenotype
absent six1.L expression in anterior placodal area
absent snai2.L expression in neural crest
absent sox10.L expression in cranial neural crest
Fig. 2 CD

Devotta A et al. (2023)
Xla Wt + npr3 MO

NF15 (in situ hybridization)
Expression Phenotype
decreased amount six1.L expression in anterior placodal area
decreased amount foxi4.1.L expression in anterior placodal area
decreased amount snai2.L expression in neural crest
decreased amount sox10.L expression in neural crest
increased amount sox2.L expression in neural plate
Fig. 4 AB

Devotta A et al. (2023)
Xla Wt + npr3 MO

NF15 (in situ hybridization)
Expression Phenotype
decreased amount six1.L expression in anterior placodal area
Fig. 3 a bottom row

Ihewulezi C and Saint-Jeannet JP (2021)
Xla Wt + hmgn1 MO

NF15 (in situ hybridization)
Expression Phenotype
decreased amount six1.L expression in neurogenic placode
decreased amount dmrta1.L expression in olfactory epithelium
decreased amount foxi4.1.L expression in neurogenic placode