Fig. S1. Periocular vascular structures are disrupted and show decreased staining for dab2 following morpholino knockdown of FRG1. Control side (A) and injected side (B) of a stage 34 embryo injected with 40 ng of FMO1. Decreased dab2 in the ocular region was found in 88% (n=18) of embryos injected with 40 ng of FMO1. Arrowheads point to dab2-expressing vessels in the ventral side of the eye and at the optic fissure, which are not present on the injected side. The arrow points to the pronephric sinus, which has been stained for dab2; the pronephric sinus cannot be detected on the injected side.
Image published in: Wuebbles RD et al. (2009)
Copyright © 2009. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| dab2.L | doc-2, xdab2 | X. laevis | Throughout NF stage 33 and 34 | head region head vasculature periocular region blood vessel pronephric sinus pronephric kidney |
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