Fig. 1. Sequence and expression profile of Xenopus MyD88. Multiple sequence alignment (A) of frog, mouse and human MyD88 (ClustalW software); light shading – isofunctional amino acids; dark shading – identical residues. Red underlining marks the Death Domain, green underlining the Toll/IL-1 receptor (TIR) homology domain. Developmental expression of XMyD88 by Northern blot (B); in comparison to histone H4 levels, used as a loading control, oocytes contain high amounts of maternal XMyD88 mRNA. Whole-mount RNA in situ hybridization at initial gastrula stage (9 hours post fertilization [hpf]; animal pole up); (C) antisense probe; (D) sense probe.
Image published in: Prothmann C et al. (2000)
Copyright © 2000. Image reproduced with permission of the Publisher, Elsevier B. V.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| myd88.L | myd88-a, myd88-b, myd88d, XMyD88 | X. laevis | Throughout NF stage 9 | animal hemisphere |
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