Figure 3. Cav1 is expressed in the nervous system during Xenopus development. (A) Immunostaining of a stage 35 embryo showing Cav1 protein expression in the notochord and the cranial nerves. (B) Dorsal view of a stage 35 embryos. Cav1 expression is visible in the cell bodies of the cranial nerve located in the brain. (C) Stage 42 embryo. (D) Higher magnification of a stage 42 embryo. Cav1 is expressed in the cranial nerves, aortic arches and the lymph heart. (D’) Image focusing on the Cav1 expression in the lung of the embryo shown in (F). (E) Ventral view of the embryo shown in (D). Cav1 staining is visible in the heart, aortic arches and cranial nerves. (F) Tail of a stage 42 embryos showing Cav1 expression in the cardio vasculature and neural tube. (G) Tail of a stage 42 embryo showing Cav1 expression in the notochord and motor neurons (H) Transverse section of the hindbrain of a stage 37 embryo showing Cav1 expression in red and DAPI staining in blue. Cav1 is expressed in neurons and the notochord. (I) Magnification of the epidermis of a stage 37 embryo. Cav1 is expressed in the deep layer of the epidermis. (J) Transverse section of the neural tube of a stage 37 embryo showing Cav1 expression in the neural tube and notochord. Aa aortic arches, Dlav dorsal longitudinal anastomosis vessel, ep epidermis, h heart, il inner layer of the epidermis, Isv/Isa intersomitic vessels/artery, lh lymph heart, lg lung, mn motor neurons, nc notochord, nt neural tube, Pcv posterior cardinal vain, so somites, sl sensory layer of the epidermis, VII facial nerve, Vop ophthalmic trigeminal ganglion, Vmd mandibular trigeminal ganglion, IX glossopharyngeal nerve, X vagus nerve.
Image published in: Breuer M et al. (2020)
© The Author(s) 2020. Creative Commons Attribution license
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| cav1.L | bscl3, Cav-1, cav1-a, cav1-b, caveolin-1, cgl3, vip21 | X. laevis | Sometime during NF stage 35 and 36 to NF stage 37 and 38 | notochord cranial nerve neural tube trigeminal ganglion |
| cav1.L | bscl3, Cav-1, cav1-a, cav1-b, caveolin-1, cgl3, vip21 | X. laevis | Throughout NF stage 42 | notochord posterior cardinal vein lung dorsal longitudinal anastomosing vessel cranial nerve right lymph heart aortic arch motor neuron neural tube |
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