Figure 5 In vivo validation of the Xenopus NRSE screen. Four F-box ubiquitin ligases identified in the NRSE screen are expressed in the neuronal tissues of X. tropicalis. A. The genomic localization of the genes with respect to NRSE motifs and B. their mRNA expression hybridization during X. tropicalis development. Gastrula embryos are ventral view with dorsal to the top. Neurula embryos are dorso-lateral view with anterior to the right. Early tailbud embryos are dorsal view with anterior to the right. Tailbud heads are lateral view with anterior to the right. The arrows point the direction of genes. Intervening genes are in turquoise. Cartoons are not to scale.
Image published in: Saritas-Yildirim B et al. (2015)
© Saritas-Yildirim et al. Creative Commons Attribution license
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| fbxo16 | fbx16 | X. tropicalis | Sometime during NF stage 22 to NF stage 28 | neural tube posterior neural tube anterior neural tube otic vesicle optic vesicle pronephric nephrostome |
| fbxo41 | LOC108706477 | X. tropicalis | Sometime during NF stage 22 to NF stage 28 | neural tube posterior neural tube anterior neural tube cranial neural crest pharyngeal arch optic vesicle eye |
| fbxl7 | X. tropicalis | Sometime during NF stage 22 to NF stage 28 | neural tube posterior neural tube anterior neural tube cranial neural crest pharyngeal arch | |
| kdm2b | fbxl10, jhdm1b | X. tropicalis | Sometime during NF stage 22 to NF stage 28 | cranial neural crest mandibular crest hyoid crest branchial crest brain forebrain midbrain hindbrain pharyngeal arch |
| fbxo16 | fbx16 | X. tropicalis | Sometime during NF stage 11 to NF stage 14 | dorsal animal hemisphere |
| fbxo41 | LOC108706477 | X. tropicalis | Throughout NF stage 11 | marginal zone |
| fbxl7 | X. tropicalis | Throughout NF stage 11 | animal hemisphere |
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