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Figure 2 Developmental expression of Xenopus NLK. (A) RT-PCR analysis shows that xNLK mRNA is maternal and expressed at all stages of early development. Lane numbers correspond to developmental stages: 0, egg; 7, 8, 9, blastula; 10.5, 12, gastrula; 20, neurula; 24, tailbud tadpole; 34, swimming tadpole. (B) Whole-mount in situ hybridization shows the localization of the xNLK transcript. xNLK transcript is distributed to the ectoderm in the early gastrula stages. Views of the vegetal pole ( left) and cross-section (right) are shown and dorsal is right (a). At the neurula ( b) and tailbud tadpole (c) stage, xNLK expression is high in the central nervous system and head. No signal is observed in a stage 32 embryo hybridized with a sense control probe (d). (C) Expression of xSox11 gene in the neural and tailbud tadpole stages. Whole-mount in situ hybridization shows that the xSox11 transcript is high in the central nervous system and head. Lateral views are shown.

Image published in: Hyodo-Miura J et al. (2002)

Copyright © 2002. Image reproduced with permission of the Publisher, John Wiley & Sons.

GeneSynonymsSpeciesStage(s)Tissue
nlk.Lnlk1, XnlkX. laevisThroughout NF stage 35 and 36central nervous system
brain
spinal cord
eye
head
pharyngeal arch
nlk.Lnlk1, XnlkX. laevisThroughout NF stage 20neural tube
posterior neural tube
anterior neural tube
nlk.Lnlk1, XnlkX. laevisThroughout NF stage 14ectoderm
dorsal
animal
sox11.Lsox11-a, sox11-b, XLS13, xls13a, XLS13b, xSOX-11, xsox11X. laevisThroughout NF stage 20neural tube
posterior neural tube
anterior neural tube
sox11.Lsox11-a, sox11-b, XLS13, xls13a, XLS13b, xSOX-11, xsox11X. laevisThroughout NF stage 35 and 36head
central nervous system
brain
spinal cord

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