Disease: visceral heterotaxy

Definition: A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.

Synonyms: heterotaxia, situs ambiguus

OMIM: MIM:306955, MIM:605376, MIM:606325, MIM:613751, MIM:614779

Reagents:

Morpholino	Experiments
cfap45 MO1	Xtr Wt + cfap45 MO Xtr Wt + cfap45 MO
cfap53 MO1	Xla Wt + cfap53 MO Xla Wt + cfap53 MO Xla Wt + cfap53 MO Xla Wt + cfap53 MO
foxj1 MO1	Xla Wt + foxj1 MO
fto MO1	Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO Xla Wt + fto MO + actinomycin D + animal cap explant
nek2 MO2	Xtr Wt + nek2 MO Xtr Wt + nek2 MO
nek2 MO3	Xtr Wt + nek2 MO Xtr Wt + nek2 MO Xtr Wt + nek2 MO Xtr Wt + nek2 MO Xtr Wt + nek2 MO Xtr Wt + nek2 MO Xtr Wt + nek2 MO Xtr Wt + nek2 MO Xtr Wt + nek2 MO
nup188 MO1	Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO Xtr Wt + nup188 MO
nup93 MO1	Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO Xtr Wt + nup93 MO
rspo2 MO1	Xla Wt + rspo2 MO Xla Wt + rspo2 MO Xla Wt + rspo2 MO - left Xla Wt + rspo2 MO - right
stk3 MO3	Xtr Wt + stk3 MO Xtr Wt + stk3 MO Xtr Wt + stk3 MO Xtr Wt + stk3 MO Xtr Wt + stk3 MO

gRNA	Experiments
cfap45 gRNA1	Xtr wt + cfap45 gRNA1
cfap45 gRNA2	Xtr Wt + cfap45 CRISPR 2
fgfr4 gRNA1	Xtr Wt + fgfr4 CRISPR
fgfr4 gRNA2	Xtr Wt + fgfr4 CRISPR
fgfr4 gRNA3	Xtr Wt + fgfr4 CRISPR
kcnh6 gRNA1	Xtr Wt + kcnh6 CRISPR (400pg) Xtr Wt + kcnh6 CRISPR (400pg)

Line	Experiments
Xtr.hps6mGrngr	Xtr.hps6mGrngr + nop BAC

Transgene	Experiments
Tg(Hsa.NEK2)	Xtr Wt + Hsa.NEK2 Xtr Wt + Hsa.NEK2 Xtr Wt + Hsa.NEK2 Xtr Wt + Hsa.NEK2 Xtr Wt + Hsa.NEK2 Xtr Wt + Hsa.NEK2
Tg(Hsa.NUP188)	Xtr Wt + Hsa.NUP188

Chemical	Experiments
Ethylnitrosourea	Xtr Wt + ENU Xtr Wt + ENU Xtr.nop x Xtr.mip
actinomycin D	Xla Wt + fto MO + actinomycin D + animal cap explant