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XB-TRANSGENE-29209198
Transgene Name | Tg(thradn) |
Description | The Xenopus DNTRα cDNA was generated by PCR by using pBluescript-TRαA,by deleting 42 base pairs (14 amino acids) from the C-terminus (Ulisse et al., 1996). DNTR binds to TH response elements but not TH and prevents transcription of TH-responsive genes by the wild-type TR in mammalian cells (Sap et al., 1989; Sakurai et al., 1990; Hao et al., 1994) and Xenopus tadpoles in vivo (Ulisse et al., 1996). |
Inducibility | None |
Components |
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