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XB-TRANSGENE-25875113
| Transgene Name | Tg(Cco.FGFR4del-Hsa.IGHG3del) |
| Description | This construct encodes a secreted form of quail FGFR4. The extracellular portion of quail FGFR4 (amino acids 1 to 282 of the GenBank Accession Number, X76885) was PCR-amplified and fused to the Fc fragment of the human immunoglobulin gamma-1 heavy chain constant region (nucleic acids 906-1803 of the GenBank sequence Accession Number, J00228). Two amino acids (G and S) introduced between FGFR4 and Fc serve as a molecular hinge for correct protein conformation. Also known as S-FR4-Fc. |
| Inducibility | None |
| Components |
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