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Summary Attributions Transgene

Line Name: Xla.Tg(hsp70:nog,cryga:GFP)Jmws

Line Images

Synonym: HGEM Noggin; HSP70-Noggin-gCrys-GFP; heat shock green-eyed monster
Species: Xenopus laevis
Background Strain: Xla.Outbred
Paternal Line:
Maternal Line:
Description: Heat shock inducible Noggin line. Noggin (nog) under control of HSP70, and gamma Crystalllin-GFP double transgenic. HGEM vector (heat shock green-eyed monster) contains a Xenopus HSP70 promoter (Marsh-Armstrong et al., 1999) upstream of a multicloning site (MCS), followed by a 6x myc tag and SV40 poly A, and the Xenopus gamma-crystallin promoter driving expression of GFP (from Rob Grainger's lab) as a visible marker for transgene insertion.
Phenotype Description: If transgenic embryos are heat shocked at stage 14 they develop multiple defects consistent with BMP inhibition, and expression of GFP in lens.
Color Morph:
Breeding Type: OUTBRED
Lab of Origin: Slack Lab
Line Type: Transgenic
Mutated Gene(s):
MTA Required: Yes
Public: Yes
Catalogue Number: EXRC line #18

Stock Center RRID Generation Availability Mutant Details Information
NXR (US) NXR_0020
EXRC (Europe) EXRC_0018
NBRP (Japan)

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