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XB-LINE-794
Line Name: Xla.Tg(hsp70:nog,cryga:GFP)Jmws
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Summary | |
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Synonym: | HGEM Noggin; HSP70-Noggin-gCrys-GFP; heat shock green-eyed monster |
Species: | Xenopus laevis |
Background Strain: | Xla.Outbred |
Paternal Line: | |
Maternal Line: | |
Description: | Heat shock inducible Noggin line. Noggin (nog) under control of HSP70, and gamma Crystalllin-GFP double transgenic. HGEM vector (heat shock green-eyed monster) contains a Xenopus HSP70 promoter (Marsh-Armstrong et al., 1999) upstream of a multicloning site (MCS), followed by a 6x myc tag and SV40 poly A, and the Xenopus gamma-crystallin promoter driving expression of GFP (from Rob Grainger's lab) as a visible marker for transgene insertion. |
Phenotype Description: | If transgenic embryos are heat shocked at stage 14 they develop multiple defects consistent with BMP inhibition, and expression of GFP in lens. |
Color Morph: | |
Breeding Type: | OUTBRED |
Lab of Origin: | Slack Lab |
Line Type: | Transgenic |
Mutated Gene(s): | |
MTA Required: | Yes |
Public: | Yes |
Catalogue Number: | EXRC line #18 |
Stock Center | RRID | Generation | Availability | Mutant Details | Information |
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NXR (US) | NXR_0020 | ||||
EXRC (Europe) | EXRC_0018 | ||||
NBRP (Japan) | |||||
XLRRI (US) |
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