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XB-LINE-1695
Line Name: Xtr.tp53em_del1/em_del2_Vlemx
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Summary | |
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Synonym: | tp53168stop |
Species: | Xtr.Nigeria |
Background Strain: | Xtr.Outbred |
Paternal Line: | |
Maternal Line: | |
Description: | Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del2/+). Both of these deletions are expected to give rise to nonsense-mediated decay since due to the frame-shifting deletion, the premRNA contains a premature stop codon (tp53168STOP). These heterozygous mutants (F1) were subsequently intercrossed to obtain F2 homozygous mutant animals. |
Phenotype Description: | |
Color Morph: | pigmented |
Breeding Type: | UNKNOWN |
Lab of Origin: | Vleminckx |
Line Type: | Mutant |
Mutated Gene(s): | tp53 |
MTA Required: | No |
Public: | Yes |
Catalogue Number: |
Stock Center | RRID | Generation | Availability | Mutant Details | Information |
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NXR (US) | |||||
EXRC (Europe) | |||||
NBRP (Japan) | |||||
XLRRI (US) |
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