Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Summary Attributions Transgene
XB-LINE-955

Line Name: Xla.Tg(rho:Eco.nfsA)Zuber

Line Images

Summary
Synonym: XOPNTR; XOP:NTR
Species: Xenopus laevis
Background Strain: Xla.Outbred
Paternal Line:
Maternal Line:
Description: rhodopsin (rho) promoter driving E. coli nitroreductase.Plasmid used for transgenesis (pXOP(-508/+41)-NTR) consists of the E. coli nitroreductase (NTR) expressed under the control of the Xenopus laevis rhodopsin promoter from Barry Knox. Base vector is pEGFP-N1 (Clontech) lacking CMV immediate early promoter & eGFP.
Phenotype Description: Expression pattern is best detected by in situ hybridization for nitroreductase transgene and is expressed specifically in rod photoreceptors Transgenic animals express nitroreductase in rod photoreceptors. Expression of the transgene has no deleterious effect on the development or survival of transgenic animals. However, addition of Metronidazole results in rapid, specific death of rod cells
Color Morph:
Breeding Type: UNKNOWN
Lab of Origin: Zuber Lab
Line Type: Transgenic
Mutated Gene(s):
MTA Required: No
Public: Yes
Catalogue Number:

Stock Center RRID Generation Availability Mutant Details Information
NXR (US) NXR_0067
EXRC (Europe)
NBRP (Japan)
XLRRI (US)

Back to Search Lines