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XB-LINE-1873
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Line Name: Xla.thrbem3NXR
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | Double CRISPR mutant line of thrb (thyroid hormone receptor, beta). Germ line transmission confirmed. Animals carry an 8 base pair deletion in thrb.L and an 8 base pair deletion in thrb.S. Contact the NXR for more details. |
| Phenotype Description: | -8 base pair mutation sequence in the L allele GATACAAGTTG--------GCACATGTGG and -8 base pair mutation sequence in S allele GATACAAGTTG--------GCACATGTGGC. Associated with human selective pituitary thyroid hormone resistance. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | NXR |
| Line Type: | Mutant |
| Mutated Gene(s): | thrb.L thrb.S |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2153 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2153 | F2+ | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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