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XB-LINE-1872
Line Name: Xla.thrbem2NXR
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Summary | |
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Synonym: | |
Species: | Xenopus laevis |
Background Strain: | Xla.J-strainNXR |
Paternal Line: | |
Maternal Line: | |
Description: | CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed. Animals carry an 8 base pair deletion in thrb.S. Custom line made for Dave Furlow. Contact the NXR for more details. |
Phenotype Description: | -8 base pair mutation sequence in S allele GATACAAGTTG--------GCACATGTGGC. Associated with human selective pituitary thyroid hormone resistance. |
Color Morph: | pigmented |
Breeding Type: | OUTBRED |
Lab of Origin: | NXR |
Line Type: | Mutant |
Mutated Gene(s): | thrb.S |
MTA Required: | No |
Public: | Yes |
Catalogue Number: | NXR_2152 |
Stock Center | RRID | Generation | Availability | Mutant Details | |
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NXR (US) | NXR_2152 | F2 | Order | ||
EXRC (Europe) | |||||
NBRP (Japan) | |||||
XLRRI (US) |
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