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Summary Attributions Transgene

Line Name: Xla.Tg(Xtr.ins:dnthra-eGFP)Brown

Synonym: pcs2::Insulin::TRDN-GFP3
Species: Xenopus laevis
Background Strain: Xla.Outbred
Paternal Line:
Maternal Line:
Description: 5.4 kb X. tropicalis insulin promoter driving dominant negative form of the thyroid receptor alpha ( (aka TRDN)) fused to GFP. The pInsulin-TRDN-GFPconstruct was made by amplifying the 5.4 kb fragment of the promoter by PCR, using primers that incorporated a Xho1 site at the 5' end and Sma1 at the 3' end, and this PCR-product was ligated into the pCS2-CMV-TRDN-flex-GFP that had been cleaved by Sal1 (at 5'and HindIII (at 3') replacing the existing CMV promoter sequence.
Phenotype Description: GFP in pancreatic Beta-cells.
Color Morph:
Breeding Type: UNKNOWN
Lab of Origin: Brown Lab
Line Type: Transgenic
Mutated Gene(s):
MTA Required: Yes
Public: Yes
Catalogue Number:

Stock Center RRID Generation Availability Mutant Details
EXRC (Europe)
NBRP (Japan)

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