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Summary Attributions Transgene

Line Name: Xla.Tg(Mmu.col1a2:dnthra-GFP)Brown

Synonym: Inducible Collagen:TRDN-GFP
Species: Xenopus laevis
Background Strain: Xla.Outbred
Paternal Line:
Maternal Line:
Description: DOX inducible. Mouse ( Mmu) collagen (col1a2) enhancer fused to a minimal collagen alpha 2 promoter drives transgene expression in many tissues of developing tadpoles. When induced with Dox, expresses a dominant negative form of the thyroid receptor alpha gene (DNthra) fused to GFP.
Phenotype Description: GFP expression in cartilage and muscle of limb. GFP expressed widely in young tadpoles, and later at tadpole stages, limb expression is restricted to cartilage and muscle. These animals die at the climax of metamorphosis, before resorbing their tail.
Color Morph:
Breeding Type: UNKNOWN
Lab of Origin: Brown Lab
Line Type: Transgenic
Mutated Gene(s):
MTA Required: Yes
Public: Yes
Catalogue Number: EXRC Line #26

Stock Center RRID Generation Availability Mutant Details
EXRC (Europe) EXRC_0026
NBRP (Japan)

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