Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Summary Attributions Transgene

Line Name: Xla.Tg.(Rno.elas:dnthra-GFP;cryga:GFP)Brown

Synonym: Elastase:TRDN-GFP; Elastase::TRDN-GFP3
Species: Xenopus laevis
Background Strain: Xla.Outbred
Paternal Line:
Maternal Line:
Description: 205 bp rat (Rno) elastase (elas) promoter driving dominant negative (DN) form of the thyroid receptor alpha (thra) (aka TRDN), fused to GFP (fusion indictated by hyphen). pElastase-TRDN-GFP construct was coinjected with Xenopus gamma-crystallin GFP (from Grainger Lab) to produce this double transgenic line.
Phenotype Description: GFP expression in the pancreas (specifically in the nucleus of the acinar cells of NF54 tadpoles), and in lens. Exocrine pancreases of transgenic tadpoles expressing a dominant negative form of the Thyroid Hormone (TH) receptor controlled by the elastase promoter are resistant to TH.
Color Morph:
Breeding Type: OUTBRED
Lab of Origin: Brown Lab
Line Type: Transgenic
Mutated Gene(s):
MTA Required: Yes
Public: Yes
Catalogue Number: waiting for EXRC RRID number

Stock Center RRID Generation Availability Mutant Details
EXRC (Europe)
NBRP (Japan)

Back to Search Lines